ExperimentalMycobacterium tuberculosisinfection in the Chinese tree shrew
نویسندگان
چکیده
منابع مشابه
Genome of the Chinese tree shrew.
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few. Here we present a publicly available annotated g...
متن کاملTree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew
The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies. With the aim to making the access to an extensively annotated ...
متن کاملidentification and characterization of liver micrornas of the chinese tree shrew via deep sequencing
conclusions according to the liver microrna data of chinese tree shrew, characteristics of the mir-122 and let-7 families further highlight the suitability of tree shrew as the animal model in hcv research. objectives this study aimed to construct a liver microrna (mirna) data of the tree shrew. materials and methods three second filial generation tree shrews were used in this study. total rna ...
متن کاملCharacterization of 12 polymorphic microsatellite markers in the Chinese tree shrew (Tupaia belangeri chinensis).
The Chinese tree shrew (Tupaia belangeri chinensis) is a small experimental animal with a close affinity to primates. This species has long been proposed to be an alternative experimental animal to primates in biomedical research. Despite decades of study, there is no pure breed for this animal, and the overall genetic diversity of wild tree shrews remains largely unknown. In order to obtain a ...
متن کاملLoss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew.
The function of the RIG-I-like receptors (RLRs; including RIG-I, MDA5, and LGP2) as key cytoplasmic sensors of viral pathogen-associated molecular patterns (PAMPs) has been subjected to numerous pathogenic challenges and has undergone a dynamic evolution. We found evolutionary evidence that RIG-I was lost in the Chinese tree shrew lineage. Along with the loss of RIG-I, both MDA5 (tMDA5) and LGP...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2014
ISSN: 0378-1097
DOI: 10.1111/1574-6968.12524